ANTIGEN OMP (OUTER MEMBRANE PROTEIN) salmonella typhi FAGA LOKAL YANG IMUNODOMINAN DAN SPESIFIK TERHADAP ANTIBODI PENDERITA DEMAM TIFOID
نویسندگان
چکیده
منابع مشابه
Identification and validation of T-cell epitopes in outer membrane protein (OMP) of Salmonella typhi
This study aims to design epitope-based peptides for the utility of vaccine development by targeting outer membrane protein F (Omp F), because two available licensed vaccines, live oral Ty21a and injectable polysaccharide, are 50% to 80% protective with a higher rate of side effects. Conventional vaccines take longer time for development and have less differentiation power between vaccinated an...
متن کاملDetection of antibodies against Salmonella typhi outer membrane protein (OMP) preparation in typhoid fever patients.
An indirect ELISA was used to detect antibodies against outer membrane protein preparations (OMPs) from Salmonella typhi. Sera from patients with a definitive diagnosis of typhoid fever (TF) gave a mean absorbance reading, at 414 nm, of 1.52 +/- 0.23 as compared to 0.30 +/- 0.11 for sera from healthy individuals. This gave a positive to negative ratio of absorbance readings of approximately 5.1...
متن کاملDot-EIA Typhoid Test Using OMP Salmonella typhi Local Phage Type Antigen
A laboratory study was carried out on 44 sera of typhoid patients (age: 15-45 years, 24 females and 20 males) with positive blood culture for S. typhi, 41 sera non typhoid febrile patients (age: 16-51 years, 17 females & 24 males) with negative blood culture and negative Widal test, 136 sera of healthy persons as normal controls (age: 20-49 years, 95 females & 41 males). The basic principle of ...
متن کاملImmune response to Vi polysaccharide, heat-killed whole cells, and outer membrane protein of Salmonella typhi.
INTRODUCTION Salmonella typhiVi capsular polysaccharide (ViCPS) is a licensed vaccine against typhoid fever in many countries; in Egypt, the killed whole-cell vaccine is still used. In this study, mice were used as an animal model to evaluate the immune response to ViCPS and other S. typhi antigens such as heat-killed whole cells and outer membrane protein (OMP). METHODOLOGY The three antigen...
متن کاملPolysaccharide Antigen of Salmonella typhi
Classical identification of S. typhi involves culture on primary agar plates and requires another 24 hours for biochemical testing. The colonies suspected to be Salmonellae will be further tested with their speci fic antisera. Most isolates of Sal monella from natural sources can be classified serologically into five groups, A to E, by a combination of multiple o (somatic), H (flagella) and V...
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ژورنال
عنوان ژورنال: INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY
سال: 2018
ISSN: 2477-4685,0854-4263
DOI: 10.24293/ijcpml.v13i3.912